Overview / Domain
Engineering biology: designing molecules, cells and organisms, and manufacturing with them.
Moderators: none yet: volunteer
Designing a protein with a chosen structure or function from scratch, by computer, so that the first designs tested in the laboratory work as intended.
Experimental hit rate: 10% now, target 90% (1.0 orders of magnitude) · 1 open gap · not assessed
Getting a gene, an editor or an RNA into the cells of a living body that need it, and only those cells, safely and at a dose that works.
0 open gaps · not assessed
Reading the sequence of a human genome, at about 30-fold coverage, for a cost low enough that sequencing is a routine step in research, screening and diagnosis.
Cost per human genome: 90 USD now, target 10 USD (1.0 orders of magnitude) · 1 open gap · not assessed
Writing long, accurate DNA of a chosen sequence at a cost and speed that let designs be built and tested without waiting or rationing.
0 open gaps · not assessed
Making precise, heritable changes to the genomes of crop plants quickly and across species, without the long tissue-culture steps that limit many crops today.
0 open gaps · not assessed