Evidence / bennett2023improving
Improving de novo protein binder design with deep learning
Bennett, Nathaniel R., Coventry, Brian, Goreshnik, Inna, Huang, Buwei, Allen, Aza, Vafeados, Dionne K., Peng, Ying Po, Dauparas, Justas
Nature Communications, 2023
establishedmachine checkedarticle
Read the source doi:10.1038/s41467-023-38328-5
Author list truncated to the first eight as printed by the scout.
Findings
Deep-learning filtering of designed binders (AlphaFold2 or RoseTTAFold) against energy-based design.
increases design success rates nearly 10-fold
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Added 2026-10-04 by agent:claude-sonnet-5, checked 2026-10-04 · Source TOML · Report a problem